Get Advances in the Immunopathogenesis of Multiple Sclerosis PDF

By Domencio Gambi,Allesandra Lugaresi,Paolo A. Muraro

ISBN-10: 884700067X

ISBN-13: 9788847000674

P.A. MURARO, A. LUGARESI, D. GAMBI the various pathological features of a number of sclerosis (MS) lesions were recognized for over a century. it is just lately, notwithstanding, that varied styles of demyelination were associated with designated pathways of immune-mediated tissue destruction. particularly, the inter-individual heterogeneity of MS lesions has urged that varied mechanisms might act in numerous sufferers, accounting for the variety saw in medical path, immunological findings in peripheral blood and cere­ brospinal fluid (CSF), and reaction to immunomodulatory remedies. to supply an summary of the fundamental mechanisms in all probability interested by MS lesion initiation and improvement, a global assembly was once equipped within the context of the yearly Congress of the Italian Neuroimmunology organization (AINI), held on the collage of Chieti, in Chieti Italy on 29 October 1998. The excessive regular of shows triggered us to file them in prolonged shape, to focus on contemporary professional­ gress within the knowing of simple mechanisms maintaining MS immuno­ pathogenesis. A valuable function within the attainable mechanisms resulting in myelin destruc­ tion has been attributed to T lymphocytes reactive to myelin antigens. stories at the myelin antigen-specific T mobilephone repertoire have contributed major advances to our wisdom of autoimmunity (Chapters 1,2).

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Advances in the Immunopathogenesis of Multiple Sclerosis by Domencio Gambi,Allesandra Lugaresi,Paolo A. Muraro

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